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Article

Characterization of Transcription from TATA-Less Promoters: Identification of a New Core Promoter Element XCPE2 and Analysis of Factor Requirements

31 Mar 2009

Abstract excerpt

BACKGROUND: More than 80% of mammalian protein-coding genes are driven by TATA-less promoters which often show multiple transcriptional start sites (TSSs). However, little is known about the core promoter DNA sequences or mechanisms of transcriptional initiation for this class of promoters. METHODOLOGY/PRINCIPAL FINDINGS: Here we identify a new core promoter element XCPE2 (X core promoter element 2) (consensus...

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PMID: 19337366
DOI: 10.1371/journal.pone.0005103

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