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Article

Multiple transcription factors in 5'-flanking region of human polymeric Ig receptor control its basal expression.

American journal of physiology. Gastrointestinal and liver physiology - 1 Aug 2002

Solorzano-Vargas R Sergio, Wang Jiafang, Jiang Lingling, Tsai Hugh V, Ontiveros Luis O, Vazir Mukta A, Aguilera Renato J, Martín Martín G

Abstract excerpt

The polymeric Ig receptor (pIgR) is a critical component of the mucosal immune system and is expressed in largest amounts in the small intestine. In this study, we describe the initial characterization of the core promoter region of this gene. Expression of chimeric promoter-reporter constructs was supported in Caco-2 and HT-29 cells, and DNase I footprint analysis revealed a large protein complex within the core...

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PMID: 12121890
DOI: 10.1152/ajpgi.00420.2001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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