Article
Cortical mapping of genotype-phenotype relationships in schizophrenia.
Human brain mapping - 1 Jun 2007
Bearden Carrie E, van Erp Theo G M, Thompson Paul M, Toga Arthur W, Cannon Tyrone D
Abstract excerpt
Although schizophrenia is highly heritable, the search for susceptibility genes has been challenging. The "endophenotype" approach is an alternative method for measuring phenotypic variation that may make it easier to identify susceptibility genes in the context of complexly inherited traits. Neuroimaging methods in particular offer a powerful way to bridge the neurobiology of genes and behavior. Such...
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