Article
Neuroimaging endophenotypes: strategies for finding genes influencing brain structure and function.
Human brain mapping - 1 Jun 2007
Glahn David C, Thompson Paul M, Blangero John
Abstract excerpt
It is vitally important to identify the genetic determinants of complex brain-related disorders such as autism, dementia, mood disorders, and schizophrenia. However, the search for genes predisposing individuals to these illnesses has been hampered by their genetic and phenotypic complexity and by reliance upon phenomenologically based qualitative diagnostic systems. Neuroimaging endophenotypes are quantitative...
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