Article
Are brain structural abnormalities useful as endophenotypes in schizophrenia?
International review of psychiatry (Abingdon, England) - 1 Aug 2007
Keshavan Matcheri S, Prasad Konasale M, Pearlson Godfrey
Abstract excerpt
Endophenotypes, which represent intermediate phenotypes on the causal pathway from the genotype to the phenotype, can help unravel the molecular etiopathology of complex psychiatric disorders such as schizophrenia. Several candidate endophenotypic markers have been proposed in schizophrenia, including neurocognitive and neurophysiological impairments. Over the past three decades, there has been an impressive body...
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