Article
Direct quantitative trait locus mapping of mammalian metabolic phenotypes in diabetic and normoglycemic rat models.
Nature genetics - 1 May 2007
Dumas Marc-Emmanuel, Wilder Steven P, Bihoreau Marie-Thérèse, Barton Richard H, Fearnside Jane F, Argoud Karène, D'Amato Lisa, Wallis Robert H, Blancher Christine, Keun Hector C, Baunsgaard Dorrit, Scott James, Sidelmann Ulla Grove, Nicholson Jeremy K, Gauguier Dominique
Abstract excerpt
Characterizing the relationships between genomic and phenotypic variation is essential to understanding disease etiology. Information-dense data sets derived from pathophysiological, proteomic and transcriptomic profiling have been applied to map quantitative trait loci (QTLs). Metabolic traits,...
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