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Application of quantitative metabolomics in systems genetics in rodent models of complex phenotypes.

Archives of biochemistry and biophysics - 1 Jan 2016

Gauguier Dominique

Abstract excerpt

Genome-wide association studies (GWAS) have provided remarkable advances in our understanding of the etiology of complex diseases in humans and have underlined the need to improve patients' phenotype characterization with intermediate molecular phenotypes. High resolution metabolomics is becoming an increasingly popular and robust strategy for metabolic phenotyping large cohorts of patients and controls in...

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PMID: 26391925
DOI: 10.1016/j.abb.2015.09.016

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