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The human immunodeficiency virus type 1 Rev protein: ménage à trois during the early phase of the lentiviral replication cycle

11 Jun 2010

Abstract excerpt

The Rev protein of human immunodeficiency viruses (HIV) has long been recognized to be essential for the late phase of the virus replication cycle, due to its strong enhancement of expression of viral structural proteins. Surprisingly, a number of recent papers have demonstrated that Rev can also interfere with integration of the reverse-transcribed cDNA into the host-cell genome. This seems to be due to Rev's...

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PMID: 20538907
DOI: 10.1099/vir.0.022509-0

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The human immunodeficiency virus type 1 Rev protein: ménage à trois during the early phase of the lentiviral replication cyclePMID 20538907Read ↗

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HIV-1 structural gene expression requires binding of the Rev trans-activator to its RNA target sequence.Semantic proximity Read ↗

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