Article
Analysis of the APOB Gene and Apolipoprotein B Serum Levels in a Mexican Population with Acute Coronary Syndrome: Association with the Single Nucleotide Variants rs1469513, rs673548, rs676210, and rs1042034.
Genetics research - 1 Jan 2022
Aceves-Ramírez Maricela, Valle Yeminia, Casillas-Muñoz Fidel, Martínez-Fernández Diana Emilia, Parra-Reyna Brenda, López-Moreno Víctor Arturo, Flores-Salinas Héctor Enrique, Valdés-Alvarado Emmanuel, Muñoz-Valle José Francisco, García-Garduño Texali, Padilla-Gutiérrez Jorge Ramón
Abstract excerpt
Apolipoprotein B (APOB) is associated with the development of atherosclerosis and consequently in the acute coronary syndrome (ACS) physiopathology. Single number variants (SNVs) in apolipoprotein B gene (APOB) influence over the susceptibility for this syndrome. The aim of this study was to determine the impact of the rs1469513, rs673548, rs676210, and rs1042034 SNVs and serum levels of APOB in the risk of ACS...