Article
CD14 C(-260)T promoter polymorphism and prevalence of acute coronary syndromes.
International journal of cardiology - 15 Feb 2005
Arroyo-Espliguero Ramón, El-Sharnouby Khaled, Vázquez-Rey Eugenia, Kalidas Kamini, Jeffery Steve, Kaski Juan Carlos
Abstract excerpt
BACKGROUND: Inflammation and infection have been implicated in atherosclerosis and its complications. The CD14 receptor mediates monocyte activation by lipopolysaccharide (LPS) of Gram-negative bacteria. The aim of this study was to assess whether the C(-260)T polymorphism in the promoter of the CD14 receptor gene is associated with a higher prevalence of acute coronary syndromes (ACS) and severity of coronary...
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