Article
Investigation of 95 variants identified in a genome-wide study for association with mortality after acute coronary syndrome.
BMC medical genetics - 29 Sept 2011
Morgan Thomas M, House John A, Cresci Sharon, Jones Philip, Allayee Hooman, Hazen Stanley L, Patel Yesha, Patel Riyaz S, Eapen Danny J, Waddy Salina P, Quyyumi Arshed A, Kleber Marcus E, März Winfried, Winkelmann Bernhard R, Boehm Bernhard O, Krumholz Harlan M, Spertus John A
Abstract excerpt
BACKGROUND: Genome-wide association studies (GWAS) have identified new candidate genes for the occurrence of acute coronary syndrome (ACS), but possible effects of such genes on survival following ACS have yet to be investigated. METHODS: We examined 95 polymorphisms in 69 distinct gene regions identified in a GWAS for premature myocardial infarction for their association with post-ACS mortality among 811 whites...
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