Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Stromal derived factor-1 exerts differential regulation on distinct cortical cell populations in vitro.

BMC developmental biology - 10 Apr 2007

Pritchett James, Wright Clare, Zeef Leo, Nadarajah Bagirathy

Abstract excerpt

BACKGROUND: Stromal derived factor (SDF-1), an alpha chemokine, is a widely known chemoattractant in the immune system. A growing body of evidence now suggests multiple regulatory roles for SDF-1 in the developing nervous system. RESULTS: To investigate the role of SDF-1 signaling in the growth and differentiation of cortical cells, we performed numerous in vitro experiments, including gene chip and quantitative...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Axons
Share to Cerebral Cortex
Share to Chemokine CXCL12

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chemokines, CXC

Share to Culture Media, Conditioned

Share to Enzyme-Linked Immunosorbent Assay

Share to Oligonucleotide Array Sequence Analysis

Share to Receptors, CXCR4

Source

Open in PubMed Open full text

Identifiers

PMID: 17425785
DOI: 10.1186/1471-213X-7-31
PMCID: PMC1854892

Genes

CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Stromal derived factor-1 exerts differential regulation on distinct cortical cell populations in vitro.PMID 17425785Read ↗

Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice.Semantic proximity Read ↗

SDF-1 involvement in endothelial phenotype and ischemia-induced recruitment of bone marrow progenitor cells.Semantic proximity Read ↗

Cloning and characterization of SDF‐1γ, a novel SDF‐1 chemokine transcript with developmentally regulated expression in the nervous systemSemantic proximity Read ↗

Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development.Semantic proximity Read ↗

A chemokine, SDF-1, reduces the effectiveness of multiple axonal repellents and is required for normal axon pathfinding.Semantic proximity Read ↗

Endothelial cell‐derived bone morphogenetic proteins regulate glial differentiation of cortical progenitorsSemantic proximity Read ↗

Foxc1 dependent mesenchymal signalling drives embryonic cerebellar growthSemantic proximity Read ↗

Role of SDF-1/CXCR4 system in survival and migration of bone marrow stromal cells after transplantation into mice cerebral infarct.Semantic proximity Read ↗

Endothelial cell-derived GABA signaling modulates neuronal migration and postnatal behavior.Semantic proximity Read ↗

Chemokine receptor CXCR4 signaling modulates the growth factor‐induced cell cycle of self‐renewing and multipotent neural progenitor cellsSemantic proximity Read ↗

Identification and expression of novel isoforms of human stromal cell-derived factor 1.Semantic proximity Read ↗

α-Chemokines Regulate Proliferation, Neurogenesis, and Dopaminergic Differentiation of Ventral Midbrain Precursors and NeurospheresSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.