Article
Role of SDF-1/CXCR4 system in survival and migration of bone marrow stromal cells after transplantation into mice cerebral infarct.
Brain research - 5 Dec 2007
Shichinohe Hideo, Kuroda Satoshi, Yano Shunsuke, Hida Kazutoshi, Iwasaki Yoshinobu
Abstract excerpt
Recent studies have indicated that bone marrow stromal cells (BMSC) have the potential to improve neurological function when transplanted into animal models of cerebral infarction. However, it is still obscure how the transplanted BMSC restore the lost neurological function. In this study, therefore, we aimed to elucidate the role of stromal cell-derived factor-1 (SDF-1) and its specific receptor, CXCR4, in BMSC...
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