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Article

Endothelial cell-derived GABA signaling modulates neuronal migration and postnatal behavior.

Cell research - 1 Feb 2018

Li Suyan, Kumar T Peeyush, Joshee Sampada, Kirschstein Timo, Subburaju Sivan, Khalili Jahan S, Kloepper Jonas, Du Chuang, Elkhal Abdallah, Szabó Gábor, Jain Rakesh K, Köhling Rüdiger, Vasudevan Anju

Abstract excerpt

The cerebral cortex is essential for integration and processing of information that is required for most behaviors. The exquisitely precise laminar organization of the cerebral cortex arises during embryonic development when neurons migrate successively from ventricular zones to coalesce into specific cortical layers. While radial glia act as guide rails for projection neuron migration, pre-formed vascular...

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PMID: 29086765
DOI: 10.1038/cr.2017.135
PMCID: PMC5799810

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