Article
SDF-1 involvement in endothelial phenotype and ischemia-induced recruitment of bone marrow progenitor cells.
Blood - 1 Dec 2004
De Falco Elena, Porcelli Daniele, Torella Anna Rita, Straino Stefania, Iachininoto Maria Grazia, Orlandi Alessia, Truffa Silvia, Biglioli Paolo, Napolitano Monica, Capogrossi Maurizio C, Pesce Maurizio
Abstract excerpt
Chemokine stromal derived factor 1 (SDF-1) is involved in trafficking of hematopoietic stem cells (HSCs) from the bone marrow (BM) to peripheral blood (PB) and has been found to enhance postischemia angiogenesis. This study was aimed at investigating whether SDF-1 plays a role in differentiation of BM-derived c-kit(+) stem cells into endothelial progenitor cells (EPCs) and in ischemia-induced trafficking of stem...
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