Article
Transgenic rescue for characterizing orphan receptors: a review of delta2 glutamate receptor.
Transgenic research - 1 Apr 2005
Yuzaki Michisuke
Abstract excerpt
Even though the genomes of several major species have been sequenced, many orphan receptors with unknown ligands and mechanisms of action remain in the CNS. The delta2 glutamate receptor (GluRdelta2) is one of such receptors expressed predominantly in the cerebellar Purkinje cells. On the basis of amino acid similarity, it belongs to ionotropic glutamate receptor (iGluR) family, which mediates fast excitatory...
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