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Article

Rescue of abnormal phenotypes of the delta2 glutamate receptor-null mice by mutant delta2 transgenes.

EMBO reports - 1 Jan 2005

Hirai Hirokazu, Miyazaki Taisuke, Kakegawa Wataru, Matsuda Shinji, Mishina Masayoshi, Watanabe Masahiko, Yuzaki Michisuke

Abstract excerpt

The delta2 glutamate receptor (GluRdelta2) has a crucial role in cerebellar functions; disruption of GluRdelta2 alleles in mice (delta2(-/-)) impairs synapse formation and long-term depression, which is thought to underlie motor learning in the cerebellum, and consequently leads to motor discoordination. However, it has been unclear whether GluRdelta2 is activated by glutamate analogues. Here we introduced a...

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Identifiers

PMID: 15592450
DOI: 10.1038/sj.embor.7400312
PMCID: PMC1299222

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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