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Article

Chromosome abnormalities with prognostic impact in B-cell chronic lymphocytic leukemia.

Pathology oncology research : POR - 1 Jan 2005

Méhes Gábor

Abstract excerpt

The detailed analysis of the biologic features led to a rapid increase in clinically relevant information in CLL. The recognition of the prognostic role of IgVH hypermutation status and related phenotypic changes (CD38, ZAP-70 expression) as well as of chromosome abnormalities defined by cytogenetic analysis enabled a refined classification of the disease. Improvements in karyotyping and the introduction of...

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Share to ADP-ribosyl Cyclase 1
Share to Chromosome Deletion
Share to Cytogenetic Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Leukemic

Share to Immunoglobulin Variable Region

Share to Karyotyping

Share to Leukemia, Lymphocytic, Chronic, B-Cell

Share to ZAP-70 Protein-Tyrosine Kinase

Source

Identifiers

PMID: 16388316
DOI: 10.1007/BF02893852

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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