Article
Tagging single nucleotide polymorphisms in cell cycle control genes and susceptibility to invasive epithelial ovarian cancer.
Cancer research - 1 Apr 2007
Gayther Simon A, Song Honglin, Ramus Susan J, Kjaer Susan Krüger, Whittemore Alice S, Quaye Lydia, Tyrer Jonathan, Shadforth Danielle, Hogdall Estrid, Hogdall Claus, Blaeker Jan, DiCioccio Richard, McGuire Valerie, Webb Penelope M, Beesley Jonathan, Green Adele C, Whiteman David C, Goodman Marc T, Lurie Galina, Carney Michael E, Modugno Francesmary, Ness Roberta B, Edwards Robert P, Moysich Kirsten B, Goode Ellen L, Couch Fergus J, Cunningham Julie M, Sellers Thomas A, Wu Anna H, Pike Malcolm C, Iversen Edwin S, Marks Jeffrey R, Garcia-Closas Montserrat, Brinton Louise, Lissowska Jolanta, Peplonska Beata, Easton Douglas F, Jacobs Ian, Ponder Bruce A J, Schildkraut Joellen, Pearce C Leigh, Chenevix-Trench Georgia, Berchuck Andrew, Pharoah Paul D P
Abstract excerpt
High-risk susceptibility genes explain <40% of the excess risk of familial ovarian cancer. Therefore, other ovarian cancer susceptibility genes are likely to exist. We have used a single nucleotide polymorphism (SNP)-tagging approach to evaluate common variants in 13 genes involved in cell cycle...
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