Article
ERCC4 associated with breast cancer risk: a two-stage case-control study using high-throughput genotyping.
Cancer research - 1 Oct 2006
Milne Roger Laughlin, Ribas Gloria, González-Neira Anna, Fagerholm Rainer, Salas Antonio, González Emilio, Dopazo Joaquín, Nevanlinna Heli, Robledo Mercedes, Benítez Javier
Abstract excerpt
The failure of linkage studies to identify further high-penetrance susceptibility genes for breast cancer points to a polygenic model, with more common variants having modest effects on risk, as the most likely candidate. We have carried out a two-stage case-control study in two European populati...
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