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Article

Association of single-nucleotide polymorphisms in the cell cycle genes with breast cancer in the British population.

Carcinogenesis - 1 Feb 2008

Driver Kristy E, Song Honglin, Lesueur Fabienne, Ahmed Shahana, Barbosa-Morais Nuno L, Tyrer Jonathan P, Ponder Bruce A J, Easton Douglas F, Pharoah Paul D P, Dunning Alison M

Abstract excerpt

Using a large-scale case-control study, we examined whether common single-nucleotide polymorphisms (SNPs) within 13 genes involved in the cell cycle pathway are associated with breast cancer risk. Seventy-nine tag SNPs were used to evaluate 240 common SNPs found in the genes: CCND1, CCND2, CCND3, CCNE1, CDK2, CDK4, CDK6, CDKN1A, CDKNIB, CDKN2A/CDKN2B, CDKN2C and CDKN2D. These were genotyped in 2270 cases and 2280...

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Source

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Identifiers

PMID: 18174243
DOI: 10.1093/carcin/bgm284
PMCID: PMC2346546

Genes

CCNE1
CCND1
CCND2
CCND3
CDK2
CDK4
CDK6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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