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Article

Tagging single-nucleotide polymorphisms in candidate oncogenes and susceptibility to ovarian cancer.

British journal of cancer - 24 Mar 2009

Quaye L, Song H, Ramus S J, Gentry-Maharaj A, Høgdall E, DiCioccio R A, McGuire V, Wu A H, Van Den Berg D J, Pike M C, Wozniak E, Doherty J A, Rossing M A, Ness R B, Moysich K B, Høgdall C, Blaakaer J, Easton D F, Ponder B A J, Jacobs I J, Menon U, Whittemore A S, Krüger-Kjaer S, Pearce C L, Pharoah P D P, Gayther S A

Abstract excerpt

Low-moderate risk alleles that are relatively common in the population may explain a significant proportion of the excess familial risk of ovarian cancer (OC) not attributed to highly penetrant genes. In this study, we evaluated the risks of OC associated with common germline variants in five oncogenes (BRAF, ERBB2, KRAS, NMI and PIK3CA) known to be involved in OC development. Thirty-four tagging SNPs in these...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19240718
DOI: 10.1038/sj.bjc.6604947
PMCID: PMC2661781

Genes

BRAF
ERBB2
KRAS
NMI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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