Article
Association of genetic variants at 8q24 with breast cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Mar 2008
Fletcher Olivia, Johnson Nichola, Gibson Lorna, Coupland Ben, Fraser Agnes, Leonard Angela, dos Santos Silva Isabel, Ashworth Alan, Houlston Richard, Peto Julian
Abstract excerpt
Recent whole genome association studies of prostate, breast, and colorectal cancer have identified susceptibility loci on 8q24. We genotyped three variants associated with prostate cancer (rs10090154, rs13254738, and rs7000448), one associated with both prostate and colorectal cancer (rs6983267), and one associated with breast cancer (rs13281615) in a series of 1,499 breast cancer cases and 1,390 controls. 1,267...