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Article

The Asp727Glu polymorphism in the TSH receptor is associated with insulin resistance in healthy elderly men.

Clinical endocrinology - 1 Jun 2007

Peeters Robin P, van der Deure Wendy M, van den Beld Annewieke W, van Toor Hans, Lamberts Steven W J, Janssen Joop A M J L, Uitterlinden André G, Visser Theo J

Abstract excerpt

BACKGROUND: Variations in thyroid function within the normal range are associated with differences in metabolism and body composition. For instance, TSH is positively associated with body mass index (BMI). This could be due to alterations in thyroid hormone activity, or to direct effects of TSH, as the TSH receptor (TSHR) is also expressed in adipose tissue. The TSHR-Asp727Glu polymorphism is associated with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17408423
DOI: 10.1111/j.1365-2265.2007.02817.x

Genes

TSHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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