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Article

The impact of a TSH receptor gene polymorphism on thyroid-related phenotypes in a healthy Danish twin population.

Clinical endocrinology - 1 Jun 2007

Hansen Pia Skov, van der Deure Wendy M, Peeters Robin P, Iachine Ivan, Fenger Mogens, Sørensen Thorkild I A, Kyvik Kirsten O, Visser Theo J, Hegedüs Laszlo

Abstract excerpt

OBJECTIVES: The Asp727Glu polymorphism in the TSH receptor (TSHR) gene is associated with serum TSH levels. However, the proportion of genetic variation accounted for by this polymorphism is unknown. In this study, we (1) examined the association of the Asp727Glu polymorphism with thyroid size, serum levels of TSH, thyroid hormones, and thyroid antibodies in 1241 healthy Danish twin individuals and (2) assessed...

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Share to Polymorphism, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Quantitative Trait, Heritable

Share to Receptors, Thyrotropin

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Source

Identifiers

PMID: 17408420
DOI: 10.1111/j.1365-2265.2007.02820.x

Genes

TSHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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