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Article

The use of meta-analysis risk estimates for candidate genes in combination to predict coronary heart disease risk.

Annals of human genetics - 1 Sept 2007

Drenos F, Whittaker J C, Humphries S E

Abstract excerpt

Although the risk for coronary heart disease (CHD) associated with single SNPs is modest it has been suggested that, in combination, several common risk-associated alleles could lead to a substantially better heart disease risk prediction. We have modelled this using 10 SNPs in ten candidate genes (APOB, NOS3, APOE, ACE, SERPINE1, MTHFR, ITGA2B, PON 1, LPL, and CETP) and their predicted summary risk estimates...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17403027
DOI: 10.1111/j.1469-1809.2007.00359.x

Genes

ACE
APOB
APOE
CETP
LPL
MTHFR
NOS3
SERPINE1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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