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Article

Individual and summed effects of high-risk genetic polymorphisms on recurrent cardiovascular events following ischemic heart disease.

Atherosclerosis - 1 Aug 2012

Andreassi Maria Grazia, Adlerstein Daniel, Carpeggiani Clara, Shehi Erlet, Fantinato Sonia, Ghezzi Elisa, Botto Nicoletta, Coceani Michele, L'abbate Antonio

Abstract excerpt

AIMS: High-risk single nucleotide polymorphisms (SNPs) have been recently identified as risk factors for ischemic heart disease in large epidemiological and genome-wide association studies. However, their influence on prognosis remains uncertain. The aim of the study was to investigate the impact of previously identified SNPs and their joint effects in a genetic score (GS) on Major Adverse Cardiac Events (MACEs)....

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Identifiers

PMID: 22717531
DOI: 10.1016/j.atherosclerosis.2012.05.029

Genes

APOC3
MTHFR
SELP

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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