Article
The risk for depression conferred by stressful life events is modified by variation at the serotonin transporter 5HTTLPR genotype: evidence from the Spanish PREDICT-Gene cohort.
Molecular psychiatry - 1 Aug 2007
Cervilla J A, Molina E, Rivera M, Torres-González F, Bellón J A, Moreno B, Luna J D, Lorente J A, Mayoral F, King M, Nazareth I, Gutiérrez B
Abstract excerpt
We report results from the PREDICT-Gene case-control study nested in a prospective cohort designed to identify predictors of the onset of depression among adult primary-care attendees. We tested the potential gene-by-environment interaction between 5HTTLPR genotype at the serotonin transporter gene and previous exposure to threatening life events (TLEs) in depression. A total of 737 consecutively recruited...
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