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Interactions between life stressors and susceptibility genes (5-HTTLPR and BDNF) on depression in Korean elders.

Biological psychiatry - 1 Sept 2007

Kim Jae-Min, Stewart Robert, Kim Sung-Wan, Yang Su-Jin, Shin Il-Seon, Kim Young-Hoon, Yoon Jin-Sang

Abstract excerpt

BACKGROUND: It has been reported that the functional polymorphism in the serotonin transporter gene linked promoter region (5-HTTLPR) modifies the association between stressful life events (SLEs) and depression in child, adolescent, and adult populations. We sought to replicate this finding in elders and, additionally, to test modifying effects of the brain-derived neurotrophic factor (BDNF) val66met...

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Identifiers

PMID: 17482146
DOI: 10.1016/j.biopsych.2006.11.020

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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