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Article

A case of loss of heterozygosity in the BRCA2 gene of a borderline ovarian tumor: case report and review of literature.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Jan 2000

Verbruggen M B, Zweemer R P, Piek J M J, van Unnik G A, van Diest P J, Gille J J P, Menko F H, Dorsman J C, Verheijen R H M

Abstract excerpt

Germline BRCA1 and BRCA2 mutations highly increase the risk of breast and female adnexal cancer. The role of these genes in the tumorigenesis of other malignancies is still under debate. Borderline ovarian tumors (BOT) are occasionally found in families with a strong history of breast and/or fema...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17386038
DOI: 10.1111/j.1525-1438.2007.00924.x

Genes

BRCA2
BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17386038-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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