Article
Mutant epidermal growth factor receptor in benign, borderline, and malignant ovarian tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jun 2008
Steffensen Karina Dahl, Waldstrøm Marianne, Olsen Dorte Aalund, Corydon Thomas, Lorentzen Karen Axelgaard, Knudsen Hans Jørgen, Jeppesen Ulla, Brandslund Ivan, Jakobsen Anders
Abstract excerpt
PURPOSE: Dysfunction of the epidermal growth factor (EGF) complex is essential to the growth and development of many human tumors. Overexpression of the EGF receptor (EGFR) is a characteristic finding in a considerable number of solid tumors and often signalizes poor prognosis. There is a major disagreement among researchers about both the frequency and possible clinical importance of EGFR overexpression in...
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