Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transgenic Mice that Express Normal and Mutated Amelogenins

1 Apr 2007

Abstract excerpt

Amelogenin proteins are secreted by ameloblasts within the enamel organ during tooth development. To better understand the function of the 180-amino-acid amelogenin (M180), and to test the hypothesis that a single proline-to-threonine (P70T) change would lead to an enamel defect similar to amelogenesis imperfecta (AI) in humans, we generated transgenic mice with expression of M180, or M180 with the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone and Dental Protein Studies
Share to dental development and anomalies
Share to Periodontal Regeneration and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17384027
DOI: 10.1177/154405910708600406

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transgenic Mice that Express Normal and Mutated AmelogeninsPMID 17384027Read ↗

Rescue of the murine amelogenin null phenotype with two amelogenin transgenes.Semantic proximity Read ↗

An amelogenin mutation leads to disruption of the odontogenic apparatus and aberrant expression of Notch1.Semantic proximity Read ↗

A Transgenic Animal Model Resembling Amelogenesis Imperfecta Related to Ameloblastin OverexpressionSemantic proximity Read ↗

The leucine-rich amelogenin peptide alters the amelogenin null enamel phenotype.Semantic proximity Read ↗

Generation and characterization of a murine amelogenesis imperfecta model.Semantic proximity Read ↗

Transgenic rescue of enamel phenotype in Ambn null mice.Semantic proximity Read ↗

The role of amelogenin during enamel-crystallite growth and organization in vivo.Semantic proximity Read ↗

M180 amelogenin processed by MMP20 is sufficient for decussating murine enamel.Semantic proximity Read ↗

A Suite of Mouse Reagents for Studying AmelogenesisSemantic proximity Read ↗

Amelogenin-deficient mice display an amelogenesis imperfecta phenotype.Semantic proximity Read ↗

Tooth enamel defects in mice with a deletion at the Arhgap 6/Amel X locus.Semantic proximity Read ↗

Alteration of conserved alternative splicing in AMELX causes enamel defects.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.