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Article

The role of amelogenin during enamel-crystallite growth and organization in vivo.

European journal of oral sciences - 1 Dec 2011

Wright J Tim, Li Yong, Suggs Cynthia, Kuehl Melissa A, Kulkarni Ashok B, Gibson Carolyn W

Abstract excerpt

Amelogenin is critical for enamel formation, and human amelogenin gene (AMELX) mutations cause hypoplastic and/or hypomaturation enamel phenotypes. The Amelx null (AKO) mouse has a severe hypoplastic phenotype. This study evaluated the effect of amelogenin loss on enamel formation and crystallite morphology. Enamel from AKO and wild-type (WT) mice was used. The AKO mice were mated with transgenic mice expressing...

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Share to Amelogenesis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22243229
DOI: 10.1111/j.1600-0722.2011.00883.x
PMCID: PMC3293103

Genes

AMELX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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