Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alteration of conserved alternative splicing in AMELX causes enamel defects.

Journal of dental research - 1 Oct 2014

Cho E S, Kim K-J, Lee K-E, Lee E-J, Yun C Y, Lee M-J, Shin T J, Hyun H-K, Kim Y-J, Lee S-H, Jung H-S, Lee Z H, Kim J-W

Abstract excerpt

Tooth enamel is the most highly mineralized tissue in vertebrates. Enamel crystal formation and elongation should be well controlled to achieve an exceptional hardness and a compact microstructure. Enamel matrix calcification occurs with several matrix proteins, such as amelogenin, enamelin, and ameloblastin. Among them, amelogenin is the most abundant enamel matrix protein, and multiple isoforms resulting from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alternative Splicing
Share to Amelogenesis Imperfecta

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Amelogenin

Share to Crystallography

Share to Dental Enamel

Share to Genetic Vectors

Share to Mice, Inbred Strains

Share to Protein Isoforms

Source

Open in PubMed Open full text

Identifiers

PMID: 25117480
DOI: 10.1177/0022034514547272
PMCID: PMC4293710

Genes

AMELX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alteration of conserved alternative splicing in AMELX causes enamel defects.PMID 25117480Read ↗

Generation and characterization of a murine amelogenesis imperfecta model.Semantic proximity Read ↗

A novel AMELX mutation causes hypoplastic amelogenesis imperfecta.Semantic proximity Read ↗

Amelogenesis Imperfecta; Genes, Proteins, and PathwaysSemantic proximity Read ↗

The origin and evolution of enamel mineralization genes.Semantic proximity Read ↗

Gene evolution and functions of extracellular matrix proteins in teethSemantic proximity Read ↗

Mutation of the gene encoding the enamel-specific protein, enamelin, causes autosomal-dominant amelogenesis imperfecta.Semantic proximity Read ↗

Evolutionary Analysis Suggests That AMTN is Enamel-specific and a Candidate for AISemantic proximity Read ↗

E<scp>namelin and</scp> A<scp>utosomal-dominant</scp> A<scp>melogenesis</scp> I<scp>mperfecta</scp>Semantic proximity Read ↗

Splicing mutations in AMELX and ENAM cause amelogenesis imperfecta.Semantic proximity Read ↗

Amelogenin p.M1T and p.W4S mutations underlying hypoplastic X-linked amelogenesis imperfecta.Semantic proximity Read ↗

AMELX Mutations and Genotype-Phenotype Correlation in X-Linked Amelogenesis Imperfecta.Semantic proximity Read ↗

Hypoplastic AI with Highly Variable Expressivity Caused by ENAM Mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.