Article
Initial load of hepatitis B virus (HBV), its changing profile, and precore/core promoter mutations correlate with the severity and outcome of acute HBV infection.
Journal of gastroenterology - 1 Mar 2007
Sainokami Shigehiko, Abe Koichi, Sato Akihiro, Endo Ryujin, Takikawa Yasuhiro, Suzuki Kazuyuki, Okamoto Hiroaki
Abstract excerpt
BACKGROUND: The pathogenesis of the fulminant or severe form of acute hepatitis B virus (HBV) infection remains unclear, although both host- and virus-specific factors are considered to have a great impact on the c course. We aimed to define possible viral factors implicated in the severe form of acute HBV infection. METHODS: We investigated viral factors in 42 patients with acute HBV infection: 11 had fulminant...
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