Article
Presence of hepatitis B virus core promoter mutations pre-seroconversion predict persistent viral replication after HBeAg loss.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Jul 2007
Ferns R Bridget, Naoumov Nikolai V, Gilson Richard J, Tedder Richard S
Abstract excerpt
BACKGROUND: In patients with chronic hepatitis B virus (HBV) infection DNA levels do not always fall after anti-hepatitis B e (anti-HBe) seroconversion. OBJECTIVES: To follow longitudinally through HB e antigen (HBeAg) loss HBV DNA levels and core promoter/precore sequences in a cohort of 21 chro...
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