Article
Clonal interference is alleviated by high mutation rates in large populations.
Molecular biology and evolution - 1 Jun 2007
Bollback Jonathan P, Huelsenbeck John P
Abstract excerpt
When a beneficial mutation is fixed in a population that lacks recombination, the genetic background linked to that mutation is fixed. As a result, beneficial mutations on different backgrounds experience competition, or "clonal interference," that can cause asexual populations to evolve more slowly than their sexual counterparts. Factors such as a large population size (N) and high mutation rates (mu) increase...
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