Article
Genetic variation and the fate of beneficial mutations in asexual populations.
Genetics - 1 Jul 2011
Lang Gregory I, Botstein David, Desai Michael M
Abstract excerpt
The fate of a newly arising beneficial mutation depends on many factors, such as the population size and the availability and fitness effects of other mutations that accumulate in the population. It has proved difficult to understand how these factors influence the trajectories of particular muta...
Topics
- Adaptation, Biological
- Evolution, Molecular
- Flow Cytometry
- Fluorescence
- Genes, Reporter
- Genetic Fitness
- Genetic Variation
- Genetics, Population
- Microscopy, Fluorescence
- Models, Genetic
- Mutation
- Population Density
- Reproduction, Asexual
- Saccharomyces cerevisiae
- Selection, Genetic