Diminishing returns of population size in the rate of RNA virus adaptation.

Abstract excerpt

Whenever an asexual viral population evolves by adapting to new environmental conditions, beneficial mutations, the ultimate cause of adaptation, are randomly produced and then fixed in the population. The larger the population size and the higher the mutation rate, the more beneficial mutations...

Topics

• Adaptation, Physiological
• Adolescent
• Animals
• Biological Evolution
• Cell Line
• Cricetinae
• Humans
• Models, Biological
• Models, Statistical
• Mutation
• Vesicular stomatitis Indiana virus
• Virus Replication