Article
Clonal interference in large populations.
Proceedings of the National Academy of Sciences of the United States of America - 13 Nov 2007
Park Su-Chan, Krug Joachim
Abstract excerpt
Clonal interference, the competition between lineages arising from different beneficial mutations in an asexually reproducing population, is an important factor determining the tempo and mode of microbial adaptation. The standard theory of this phenomenon neglects the occurrence of multiple mutations as well as the correlation between loss by genetic drift and clonal competition, which is questionable in large...
Topics
- Adaptation, Physiological
- Microbiology
- Models, Theoretical
- Mutation