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Article

Clonal interference and the evolution of RNA viruses.

Science (New York, N.Y.) - 10 Sept 1999

Miralles R, Gerrish P J, Moya A, Elena S F

Abstract excerpt

In asexual populations, beneficial mutations that occur in different lineages compete with one another. This phenomenon, known as clonal interference, ensures that those beneficial mutations that do achieve fixation are of large effect. Clonal interference also increases the time between fixations, thereby slowing the adaptation of asexual populations. The effects of clonal interference were measured in the...

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Identifiers

PMID: 10481012
DOI: 10.1126/science.285.5434.1745

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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