Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Beneficial mutations and the dynamics of adaptation in asexual populations.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 27 Apr 2010

Sniegowski Paul D, Gerrish Philip J

Abstract excerpt

We discuss the dynamics of adaptive evolution in asexual (clonal) populations. The classical 'periodic selection' model of clonal evolution assumed that beneficial mutations are very rare and therefore substitute unfettered into populations as occasional, isolated events. Newer models allow for the possibility that beneficial mutations are sufficiently common to coexist and compete for fixation within...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacteria
Share to Clone Cells
Share to Genetics, Population

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Models, Genetic

Share to Mutation

Share to Reproduction, Asexual

Share to Selection, Genetic

Share to Stochastic Processes

Source

Open in PubMed Open full text

Identifiers

PMID: 20308101
DOI: 10.1098/rstb.2009.0290
PMCID: PMC2871819

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Beneficial mutations and the dynamics of adaptation in asexual populations.PMID 20308101Read ↗

The fate of competing beneficial mutations in an asexual population.Semantic proximity Read ↗

Fitness effects of fixed beneficial mutations in microbial populations.Semantic proximity Read ↗

The speed of evolution and maintenance of variation in asexual populations.Semantic proximity Read ↗

Clonal interference, multiple mutations and adaptation in large asexual populations.Semantic proximity Read ↗

Adaptation in sexuals vs. asexuals: clonal interference and the Fisher-Muller model.Semantic proximity Read ↗

Distribution of fixed beneficial mutations and the rate of adaptation in asexual populations.Semantic proximity Read ↗

Clonal interference and the periodic selection of new beneficial mutations in Escherichia coli.Semantic proximity Read ↗

Mutational effects on the clonal interference phenomenon.Semantic proximity Read ↗

The adaptation rate of asexuals: deleterious mutations, clonal interference and population bottlenecks.Semantic proximity Read ↗

Clonal interference in large populations.Semantic proximity Read ↗

The distribution of beneficial mutant effects under strong selection.Semantic proximity Read ↗

The influence of deleterious mutations on adaptation in asexual populations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.