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Article

Augmentation of NZB autoimmune phenotypes by the Sle1c murine lupus susceptibility interval.

Journal of immunology (Baltimore, Md. : 1950) - 1 Apr 2007

Giles Brendan M, Tchepeleva Svetlana N, Kachinski Julie J, Ruff Katherine, Croker Byron P, Morel Laurence, Boackle Susan A

Abstract excerpt

The Sle1c lupus susceptibility interval spans a 7-Mb region on distal murine chromosome 1. Cr2 is the strongest candidate gene for lupus susceptibility in this interval, as its protein products are structurally and functionally altered. B6.Sle1c congenic mice develop Abs to chromatin by 9 mo of age with a 30% penetrance and do not develop GN. To determine whether the New Zealand White (NZW)-derived Sle1c interval...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17372026
DOI: 10.4049/jimmunol.178.7.4667

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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