Article
A genome-wide linkage scan for ankle-brachial index in African American and non-Hispanic white subjects participating in the GENOA study.
Atherosclerosis - 1 Aug 2006
Kullo Iftikhar J, Turner Stephen T, Kardia Sharon L R, Mosley Thomas H, Boerwinkle Eric, de Andrade Mariza
Abstract excerpt
Little is known about the genetics of peripheral arterial disease (PAD). We performed linkage analyses to identify genomic regions that influence ankle-brachial index (ABI), a measure of PAD, in 1310 African Americans (AA) (mean age 62+/-9 years) and 796 non-Hispanic whites (NHW) (mean age 58+/-9 years) belonging to hypertensive sibships. ABI was determined at two sites in each lower extremity and the lower of...
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