Article
Sequence changes of infectious bronchitis virus isolates in the 3' 7.3 kb of the genome after attenuating passage in embryonated eggs.
Avian pathology : journal of the W.V.P.A - 1 Feb 2007
Huang Yuan-Pin, Wang Ching-Ho
Abstract excerpt
Attenuated infectious bronchitis virus (IBV) vaccines are available but the relationship between sequence and virulence is not clear. In this study, the sequences of the 3' 7.3 kb of the genome, amplified using reverse transcription-polymerase chain reaction before and after attenuation, were compared to study the relationship between virulence and the sequences of three IBV strains. After attenuation, two to six...
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