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Article

Changes in VP3 and VP5 genes during the attenuation of the very virulent infectious bursal disease virus strain Gx isolated in China.

Virus genes - 1 Jan 2007

Wang Xiaomei, Zhang Houshuang, Gao Honglei, Fu Chaoyang, Gao Yulong, Ju Yulin

Abstract excerpt

A very virulent infectious bursal disease virus (vvIBDV) Gx strain with high pathogenicity was attenuated through replication in specific-pathogen free (SPF) chicken embryos and in chicken embryo fibroblast (CEF) cell cultures. The changes in nucleotide sequences and the deduced amino acid sequences of VP3 and VP5 genes during attenuation were obtained. Sequence analysis of selected passages from numbers 0 to 20...

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PMID: 16917739
DOI: 10.1007/s11262-006-0002-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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