Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Attenuation mechanism of virulent infectious bronchitis virus strain with QX genotype by continuous passage in chicken embryos.

Vaccine - 2 Jan 2016

Huo Ya-fei, Huang Qing-hua, Lu Mei, Wu Jia-qiang, Lin Shu-qian, Zhu Fengzhu, Zhang Xiu-mei, Huang Yan-yan, Yang Shao-hua, Xu Chuan-tian

Abstract excerpt

The virulent isolate SDZB0808 of QX-type infectious bronchitis virus (IBV) was continuously passaged in chicken embryos for 110 generations. The safety and immune efficacy of the 110th generation of IBVs (P110) were evaluated. Damage was not found in the appearance of the 3-day-old specific-pathogen-free (SPF) chicks immunized with 10(4.5) EID50 (median embryo infective dose) of P110 by intranasal and ocular...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Administration, Intranasal
Share to Coronavirus Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug-Related Side Effects and Adverse Reactions

Share to Infectious bronchitis virus

Share to RNA-Dependent RNA Polymerase

Share to Serial Passage

Share to Vaccines, Attenuated

Share to Viral Vaccines

Source

Identifiers

PMID: 26611202
DOI: 10.1016/j.vaccine.2015.11.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Attenuation mechanism of virulent infectious bronchitis virus strain with QX genotype by continuous passage in chicken embryos.PMID 26611202Read ↗

Construction of chicken infectious anemia virus infectious clone and study on its pathogenicitySemantic proximity Read ↗

Pathogenicity evaluation of GVI-1 lineage infectious bronchitis virus and its long-term effects on reproductive system development in SPF hensSemantic proximity Read ↗

Molecular characteristic, evolution, and pathogenicity analysis of avian infectious bronchitis virus isolates associated with QX type in ChinaSemantic proximity Read ↗

Deciphering the Genetic Variation: A Comparative Analysis of Parental and Attenuated Strains of the QXL87 Vaccine for Infectious BronchitisSemantic proximity Read ↗

Molecular characteristics and pathogenicity analysis of QX-like avian infectious bronchitis virus isolated in China in 2017 and 2018Semantic proximity Read ↗

Identification of a novel avian coronavirus infectious bronchitis virus variant with three-nucleotide-deletion in nucleocapsid gene in China.Semantic proximity Read ↗

Pathogenicity comparison between QX-type and Mass-type infectious bronchitis virus to different segments of the oviducts in laying phaseSemantic proximity Read ↗

Pathogenicity of a QX-like strain of infectious bronchitis virus and effects of accessory proteins 3a and 3b in chickensSemantic proximity Read ↗

Changes in VP3 and VP5 genes during the attenuation of the very virulent infectious bursal disease virus strain Gx isolated in China.Semantic proximity Read ↗

Pathogenicity Comparison Between QX-Type And Mass-Type Infectious Bronchitis Virus To Different Segments of The Oviducts In Laying PhaseSemantic proximity Read ↗

Changes in VP2 Gene During the Attenuation of Very Virulent Infectious Bursal Disease Virus Strain Gx Isolated in ChinaSemantic proximity Read ↗

Genetic and pathogenic characteristics of a novel infectious bronchitis virus strain in genogroup VI (CK/CH/FJ/202005).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.