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Article

Involvement of the leader sequence in Sendai virus pathogenesis revealed by recovery of a pathogenic field isolate from cDNA.

Journal of virology - 1 Sept 2002

Fujii Yutaka, Sakaguchi Takemasa, Kiyotani Katsuhiro, Huang Cheng, Fukuhara Noriko, Egi Yoshiko, Yoshida Tetsuya

Abstract excerpt

We previously demonstrated that a systematic passage of a pathogenic field isolate of Sendai virus (SeV), the Hamamatsu strain, in embryonated eggs caused attenuation of virulence to mice, and we isolated viral clones of distinct virulence (K. Kiyotani et al. Arch. Virol. 146:893-908, 2001). One of the clones, E15cl2, which was obtained from the virus at the 15th egg passage of E0, the parental Hamamatsu clone...

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Identifiers

PMID: 12163573
DOI: 10.1128/jvi.76.17.8540-8547.2002
PMCID: PMC136997

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