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Article

TGF-beta1 polymorphisms and arterial stiffness; the Rotterdam Study.

Journal of human hypertension - 1 Jun 2007

Sie M P S, Mattace-Raso F U S, Uitterlinden A G, Arp P P, Hofman A, Hoeks A P G, Reneman R S, Asmar R, van Duijn C M, Witteman J C M

Abstract excerpt

Arterial stiffness is a risk factor for cardiovascular disease. Transforming growth factor beta1 is a pleiotropic cytokine, with many functions, including influence on the vascular wall (e.g., on angiogenesis, endothelial cells and the extracellular matrix). We investigated five functional polymorphisms in the transforming growth factor beta1 gene (-800 G/A, -509 C/T, codon 10 Leu/Pro, codon 25 Arg/Pro and codon...

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PMID: 17361195
DOI: 10.1038/sj.jhh.1002175

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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