Article
A multilocus genetic risk score is associated with arterial stiffness in hypertensive patients: the CARE NORTH study.
Journal of hypertension - 1 Sept 2018
Polonis Katarzyna, Hoffmann Michal, Szyndler Anna, Wolf Jacek, Nowak Robert, Becari Christiane, Laurent Stephane, Boutouyrie Pierre, Melander Olle, Narkiewicz Krzysztof
Abstract excerpt
INTRODUCTION: Arterial stiffness is recognized as an intermediate phenotype and predictor of cardiovascular disease. Arterial stiffness is complex in origin with contributions from lifestyle and genetic factors. However, the association between single nucleotide polymorphisms (SNPs) and arterial stiffness remains unclear. OBJECTIVE: The aim is to assess whether a multilocus genetic risk score (GRS), composed of...
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